Jun 17, 2024
Expansion microscopy technique optimized for viewing meiotic protein structures
By Dr. Stefanie Chen By testing three different expansion protocols (ProExM, MAP, and U-ExM) and using three types of super-resolution microscopy (dSTORM, SIM, and re-scan confocal microscopy), researchers were able to determine that MAP-SIM worked best for imaging the fine features of the meiosis-specific synaptonemal complex from mouse spermatocytes. In order to view small molecular…